Ksilitol oksidaza
Ksilitol oksidaza (EC 1.1.3.41, ksilitolna oksidaza, ksilitol:kiseonik oksidoreduktaza, AldO) je enzim sa sistematskim imenom alditol:kiseonik oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Ksilitol oksidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.3.41 | ||||||||
| CAS broj | 177322-52-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzim iz Streptomyces vrste IKD472 i iz Streptomyces coelicolor je monomerna oksidaza koja sadrži jedan molekul FAD-a po molekulu proteina. Ksilitol i sorbitol su preferentni supstrati.
Reference уреди
- ^ Yamashita, M., Omura, H., Okamoto, E., Furuya, Y., Yabuuchi, M., Fukahi, K. and Murooka, Y. (2000). „Isolation, characterization, and molecular cloning of a thermostable xylitol oxidase from Streptomyces sp. IKD472”. J. Biosci. Bioeng. 89: 350—360. PMID 16232758.
- ^ Heuts, D.P., van Hellemond, E.W., Janssen, D.B. and Fraaije, M.W. (2007). „Discovery, characterization, and kinetic analysis of an alditol oxidase from Streptomyces coelicolor”. J. Biol. Chem. 282: 20283—20291. PMID 17517896.
- ^ Forneris, F., Heuts, D.P., Delvecchio, M., Rovida, S., Fraaije, M.W. and Mattevi, A. (2008). „Structural analysis of the catalytic mechanism and stereoselectivity in Streptomyces coelicolor alditol oxidase”. Biochemistry. 47: 978—985. PMID 18154360.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Alditol+oxidase на US National Library of Medicine Medical Subject Headings (MeSH)
