Diaminobutirat acetiltransferaza
(преусмерено са L-2,4-diaminobutanoatna acetiltransferaza)
Diaminobutirat acetiltransferaza (EC 2.3.1.178, L-2,4-diaminobutiratna acetiltransferaza, L-2,4-diaminobutanoatna acetiltransferaza, EctA, acetiltransferaza diaminobutirne kiseline, DABA acetiltransferaza, 2,4-diaminobutanoatna acetiltransferaza, DAB acetiltransferaza, DABAcT, acetil-KoA:L-2,4-diaminobutanoatna 4-N-acetiltransferaza) je enzim sa sistematskim imenom acetil-KoA:L-2,4-diaminobutanoat N4-acetiltransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Diaminobutirat acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.178 | ||||||||
| CAS broj | 130456-92-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- acetil-KoA + L-2,4-diaminobutanoat KoA + N4-acetil-L-2,4-diaminobutanoat
Za rad ovog enzima je neophodan jon Na+ ili K+ za maksimalnu aktivnost.
Reference уреди
- ^ Peters, P., Galinski, E.A. and Truper, H.G. (1990). „The biosynthesis of ectoine”. FEMS Microbiol. Lett. 71: 157—162.
- ^ Ono, H., Sawada, K., Khunajakr, N., Tao, T., Yamamoto, M., Hiramoto, M., Shinmyo, A., Takano, M. and Murooka, Y. (1999). „Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata”. J. Bacteriol. 181: 91—99. PMID 9864317.
- ^ Reshetnikov, A.S., Mustakhimov, I.I., Khmelenina, V.N. and Trotsenko, Y.A. (2005). „Cloning, purification, and characterization of diaminobutyrate acetyltransferase from the halotolerant methanotroph Methylomicrobium alcaliphilum 20Z”. Biochemistry (Mosc). 70: 878—883. PMID 16212543.
- ^ Kuhlmann, A.U. & Bremer, E. (2002). „Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp”. Appl. Environ. Microbiol. 68: 772—783. PMID 11823218.
- ^ Louis, P. & Galinski, E.A. (1997). „Characterization of genes for the biosynthesis of the compatible solute ectoine from Marinococcus halophilus and osmoregulated expression in Escherichia coli”. Microbiology. 143: 1141—1149. PMID 9141677.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Diaminobutyrate+acetyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
