Leucin N-acetiltransferaza
Leucin N-acetiltransferaza (EC 2.3.1.66, leucinska acetiltransferaza) je enzim sa sistematskim imenom acetil-KoA:L-leucin N-acetiltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Leucin N-acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.66 | ||||||||
| CAS broj | 75496-56-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- acetil-KoA + L-leucin KoA + N-acetil-L-leucin
Propanoil-KoA može da deluje kao donor, mada sporije. L-arginin, L-valin, L-fenilalanin i peptidi koji sadrže L-leucin modu da deluju kao akceptors.
Reference
уреди- ^ Suzukake, S., Hayashi, H., Hori, M. and Umezawa, H. (1982). „Biosnthesis of leupeptin III. Isolation and properties of an enzyme synthesizing acetyl-L-leucine”. J. Antibiot. 33: 857—862.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Leucine+N-acetyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
