Leukotrienska C4 hidrolaza
Leukotrienska C4 hidrolaza (EC 3.4.19.14, gama-glutamilna leukotrienaza, GGT5) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Leukotrienska C4 hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.19.14 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- leukotrien C4 + H2O leukotrien D4 + L-glutamat
Ovaj mišji enzim je specifičan za leukotrien C4.
Reference уреди
- ^ Carter, B.Z., Wiseman, A.L., Orkiszewski, R., Ballard, K.D., Ou, C.N. and Lieberman, M.W. (1997). „Metabolism of leukotriene C4 in γ-glutamyl transpeptidase-deficient mice”. J. Biol. Chem. 272: 12305—12310. PMID 9139674.
- ^ Shi, Z.Z., Han, B., Habib, G.M., Matzuk, M.M. and Lieberman, M.W. (2001). „Disruption of γ-glutamyl leukotrienase results in disruption of leukotriene D4 synthesis in vivo and attenuation of the acute inflammatory response”. Mol. Cell Biol. 21: 5389—5395. PMID 11463821.
- ^ Han, B., Luo, G., Shi, Z.Z., Barrios, R., Atwood, D., Liu, W., Habib, G.M., Sifers, R.N., Corry, D.B. and Lieberman, M.W. (2002). „γ-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D4 formation in vivo”. Am J Pathol. 161: 481—490. PMID 12163373.
- ^ Wickham, S., West, M.B., Cook, P.F. and Hanigan, M.H. (2011). „Gamma-glutamyl compounds: substrate specificity of γ-glutamyl transpeptidase enzymes”. Anal. Biochem. 414: 208—214. PMID 21447318.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Leukotriene-C4+hydrolase на US National Library of Medicine Medical Subject Headings (MeSH)
