Limulusni zgrušavajući enzim
Limulusni zgrušavajući enzim (EC 3.4.21.86, enzim zgrušavanja) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Limulusni zgrušavajući enzim | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.86 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Selektivno razlaganje -Arg18- i -Arg47- veza u koagulogenu čime se formiraju koagulin i fragmenti
Ovaj enzim je izolovan iz hemocitnih granula vrsta rakova Limulus i Tachypleus.
Reference
уреди- ^ Muta, T., Hashimoto, R., Miyata, T., Nishimura, H., Toh, Y. and Iwanaga, S. (1990). „Proclotting enzyme from horseshoe crab hemocytes. cDNA cloning, disulfide locations, and subcellular localization”. J. Biol. Chem. 265: 22426—22433. PMID 2266134.
- ^ Tokunaga, F., Nakajima, H. and Iwanaga, S. (1991). „Further studies on lipopolysaccharide-sensitive serine protease zymogen (factor C): its isolation from Limulus polyphemus hemocytes and identification as an intracellular zymogen activated by α-chymotrypsin, not by trypsin”. J. Biochem. (Tokyo). 109: 150—157. PMID 2016264.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Limulus+clotting+enzyme на US National Library of Medicine Medical Subject Headings (MeSH)
