Manozilglicerat sintaza
Manozilglicerat sintaza (EC 2.4.1.269) je enzim sa sistematskim imenom GDP-manoza:D-glicerat 2-alfa-D-manoziltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Manozilglicerat sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.269 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- GDP-manoza + D-glicerat GDP + 2-O-(alfa-D-manopiranozil)-D-glicerat
Rhoddrugemus marinus može takođe da formira manozilglicerat putem reakcije koja teče u dva koraka katalizovana enzimima EC 2.4.1.217 (manozil-3-fosfoglicerat sintaza) i EC 3.1.3.70 (manozil-3-fosfoglicerat fosfataza).
Reference уреди
- ^ Martins, L.O., Empadinhas, N., Marugg, J.D., Miguel, C., Ferreira, C., da Costa, M.S. and Santos, H. (1999). „Biosynthesis of mannosylglycerate in the thermophilic bacterium Rhodothermus marinus. Biochemical and genetic characterization of a mannosylglycerate synthase”. J. Biol. Chem. 274: 35407—35414. PMID 10585410.
- ^ Flint, J., Taylor, E., Yang, M., Bolam, D.N., Tailford, L.E., Martinez-Fleites, C., Dodson, E.J., Davis, B.G., Gilbert, H.J. and Davies, G.J. (2005). „Structural dissection and high-throughput screening of mannosylglycerate synthase”. Nat. Struct. Mol. Biol. 12: 608—614. PMID 15951819.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Mannosylglycerate+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
