Metilmalonil-KoA dekarboksilaza
Metilmalonil-KoA dekarboksilaza (EC 4.1.1.41, propionil koenzim A karboksilaza, metilmalonil-koenzim A dekarboksilaza, (S)-2-metil-3-oksopropanoil-KoA karboksilijaza, (S)-metilmalonil-KoA karboksilijaza) je enzim sa sistematskim imenom (S)-metilmalonil-KoA karboksilijaza (formira propanoil-KoA).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Metilmalonil-KoA dekarboksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Metilmalonil-KoA dekarboksilaza trimer, E.Coli | |||||||||
| Identifikatori | |||||||||
| EC broj | 4.1.1.41 | ||||||||
| CAS broj | 37289-44-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (S)-metilmalonil-KoA propanoil-KoA + CO2
Enzim iz Veillonella alcalescens je biotinski protein.
Reference уреди
- ^ Galivan, J.H. & Allen, S.H.G. (1968). „Methylmalonyl coenzyme A decarboxylase. Its role in succinate decarboxylation by Micrococcus lactilyticus”. J. Biol. Chem. 243: 1253—1261. PMID 5646172.
- ^ Hilpert, W. & Dimroth, P. (1982). „Conversion of the chemical energy of methylmalonyl-CoA decarboxylation into a Na+ gradient”. Nature. 296: 584—585. PMID 7070502.
- ^ Hoffmann, A., Hilpert, W. and Dimroth, P. (1989). „The carboxyltransferase activity of the sodium-ion-translocating methylmalonyl-CoA decarboxylase of Veillonella alcalescens”. Eur. J. Biochem. 179: 645—650. PMID 2920730.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Methylmalonyl-CoA+decarboxylase на US National Library of Medicine Medical Subject Headings (MeSH)
