Metilornitinska sintaza
Metilornitinska sintaza (EC 5.4.99.58, PylB) je enzim sa sistematskim imenom L-lizin karboksi-aminometilmutaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Metilornitinska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.4.99.58 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- L-lizin (3R)-3-metil-D-ornitin
Ovaj enzim je član superfamilije S-adenozil-L-metionin-zavisnih radikalskih enzima.
Reference
уреди- ^ Gaston, M.A., Zhang, L., Green-Church, K.B. and Krzycki, J.A. (2011). „The complete biosynthesis of the genetically encoded amino acid pyrrolysine from lysine”. Nature. 471: 647—650. PMID 21455182.
- ^ Quitterer, F., List, A., Eisenreich, W., Bacher, A. and Groll, M. (2012). „Crystal structure of methylornithine synthase (PylB): insights into the pyrrolysine biosynthesis”. Angew. Chem. Int. Ed. Engl. 51: 1339—1342. PMID 22095926.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Methylornithine+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
