Mieloblastin
Mieloblastin (EC 3.4.21.76, leukocitna proteinaza 3, leukocitna proteinaza 4, Vegenerov granulomatozni autoantigen, proteinaza PR-3, proteinaza-3, PMNL proteinaza) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Mieloblastin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.76 | ||||||||
| CAS broj | 128028-50-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzim je prisutan u polimorfonuklearnim leukocitnim granulama.
Reference уреди
- ^ Labbaye, C., Musette, P. and Cayre, Y.E. (1991). „Wegener autoantigen and myeloblastin are encoded by a single mRNA”. Proc. Natl. Acad. Sci. USA. 88: 9253—9256. PMID 1681549.
- ^ Rao, N.V., Wehner, N.G., Marshall, B.C., Gray, W.R., Gray, B.H. and Hoidal, J.R. (1991). „Characterization of proteinase-3 (PR-3), a neutrophil serine proteinase. Structural and functional properties”. J. Biol. Chem. 266: 9540—9548. PMID 2033050.
- ^ Brubaker, M.J., Groutas, W.C., Hoidal, J.R. and Rao, N.V. (1992). „Human neutrophil proteinase 3: mapping of the substrate binding site using peptidyl thiobenzyl esters”. Biochem. Biophys. Res. Commun. 188: 1318—1324. PMID 1445363.
- ^ Kam, C.-M., Kerrigan, J.E., Dolman, K.M., Goldschmeding, R., von dem Borne, A.E.G.K. and Powers, J.C. (1992). „Substrate and inhibitor studies on proteinase 3”. FEBS Lett. 297: 119—123. PMID 1551417.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Myeloblastin на US National Library of Medicine Medical Subject Headings (MeSH)
