Mikolizin
Mikolizin (EC 3.4.24.31, pronazna komponenta, Streptomyces griseus neutralna proteinaza, aktinaza E, SGNPI) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Mikolizin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.31 | ||||||||
| CAS broj | 153190-34-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Preferentno razlaganje veza sa hidrofobnim ostatacima u P1'
Ovaj enzim je prisutan u bakterijama Streptomyces griseus, S. naraensis, i S. cacaoi.
Reference
уреди- ^ Morihara, K., Tsuzuki, H. and Oka, T. (1968). „Comparison of the specificities of various neutral proteinases from microorganisms”. Arch. Biochem. Biophys. 123: 572—588. PMID 4967801.
- ^ Hiramatsu, A. & Ouchi, T. (1972). „A neutral proteinase from Streptomyces naraensis”. J. Biochem. (Tokyo). 71: 767—781. PMID 5073323.
- ^ Blumberg, S. & Tauber, Z. (1983). „Inhibition of metalloendopeptidases by 2-mercaptoacetyl-dipeptides”. Eur. J. Biochem. 136: 151—154. PMID 6413206.
- ^ Chang, P.C., Kue, T-C., Tsugita, A. and Lee, Y.H.W. (1990). „Extracellular metalloprotease gene of Streptomyces cacaoi: structure, nucleotide sequence and characterization of the cloned gene product”. Gene. 88: 87—95. PMID 2341042.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
