Molibdopterin molibdotransferaza
Molibdopterin molibdotransferaza (EC 2.10.1.1, MoeA, Cnx1) je enzim sa sistematskim imenom adenilil-molibdopterin:molibdat molibdat transferaza (formira AMP).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Molibdopterin molibdotransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.10.1.1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- adenilil-molibdopterin + molibdat molibdenski kofaktor + AMP
Ovaj enzim katalizuje umetanje molibdena u en-ditiol grupu molibdopterina.
Reference
уреди- ^ Nichols, J.D. & Rajagopalan, K.V. (2005). „In vitro molybdenum ligation to molybdopterin using purified components”. J. Biol. Chem. 280: 7817—7822. PMID 15632135.
- ^ Nichols, J.D., Xiang, S., Schindelin, H. and Rajagopalan, K.V. (2007). „Mutational analysis of Escherichia coli MoeA: two functional activities map to the active site cleft”. Biochemistry. 46: 78—86. PMID 17198377.
- ^ Llamas, A., Otte, T., Multhaup, G., Mendel, R.R. and Schwarz, G. (2006). „The Mechanism of nucleotide-assisted molybdenum insertion into molybdopterin. A novel route toward metal cofactor assembly”. J. Biol. Chem. 281: 18343—18350. PMID 16636046.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Molybdopterin+molybdotransferase на US National Library of Medicine Medical Subject Headings (MeSH)
