N-sukcinilargininska dihidrolaza
N-sukcinilargininska dihidrolaza (EC 3.5.3.23, N2-sukcinilargininska dihidrolaza, argininska sukcinilhidrolaza, SADH, AruB, AstB, 2-N-sukcinil-L-arginin iminohidrolaza (dekarboksilacija)) je enzim sa sistematskim imenom N2-sukcinil-L-arginin iminohidrolaza (dekarboksilacija).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| N-sukcinilargininska dihidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.3.23 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- N2-sukcinil-L-arginin + 2H2O N2-sukcinil-L-ornitin + 2 NH3 + CO2
Arginin, N2-acetilarginin i N2-glutamilarginin nisu supstrati.
Reference уреди
- ^ Schneider, B.L., Kiupakis, A.K. and Reitzer, L.J. (1998). „Arginine catabolism and the arginine succinyltransferase pathway in Escherichia coli”. J. Bacteriol. 180: 4278—4286. PMID 9696779.
- ^ Tocilj, A., Schrag, J.D., Li, Y., Schneider, B.L., Reitzer, L., Matte, A. and Cygler, M. (2005). „Crystal structure of N-succinylarginine dihydrolase AstB, bound to substrate and product, an enzyme from the arginine catabolic pathway of Escherichia coli”. J. Biol. Chem. 280: 15800—15808. PMID 15703173.
- ^ Vander Wauven, C. & Stalon, V. (1985). „Occurrence of succinyl derivatives in the catabolism of arginine in Pseudomonas cepacia”. J. Bacteriol. 164: 882—886. PMID 2865249.
- ^ Cunin, R., Glansdorff, N., Pierard, A. and Stalon, V. (1986). „Biosynthesis and metabolism of arginine in bacteria”. Microbiol. Rev. 50: 314—352. PMID 3534538.
- ^ Itoh, Y. (1997). „Cloning and characterization of the aru genes encoding enzymes of the catabolic arginine succinyltransferase pathway in Pseudomonas aeruginosa”. J. Bacteriol. 179: 7280—7290. PMID 9393691.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- N-succinylarginine+dihydrolase на US National Library of Medicine Medical Subject Headings (MeSH)
