O-fosfo-L-serin—tRNK ligaza
O-fosfo-L-serin—tRNK ligaza (EC 6.1.1.27, O-fosfoseril-tRNK ligaza, nekanonička O-fosfoseril-tRNK sintetaza, SepRS) je enzim sa sistematskim imenom O-fosfo-L-serin:tRNKCis ligaza(formira AMP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
O-fosfo-L-serin—tRNK ligaza | |||||||||
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Identifikatori | |||||||||
EC broj | 6.1.1.27 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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U organizmima poput Archaeoglobus fulgidus Cys-tRNKCys se formira indirektnim putem.
Reference уреди
- ^ Fukunaga, R. & Yokoyama, S. (2007). „Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea”. Nat. Struct. Mol. Biol. 14: 272—279. PMID 17351629.
- ^ Hauenstein, S.I. & Perona, J.J. (2008). „Redundant synthesis of cysteinyl-tRNACys in Methanosarcina mazei”. J. Biol. Chem. 283: 22007—22017. PMID 18559341.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- O-phospho-L-serine---tRNA+ligase на US National Library of Medicine Medical Subject Headings (MeSH)