O-fosfoserin sulfhidrilaza
O-fosfoserin sulfhidrilaza (EC 2.5.1.65, O-fosfoserin(tiol)-lijaza) je enzim sa sistematskim imenom O-fosfo-L-serin:vodonik-sulfid 2-amino-2-karboksietiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| O-fosfoserin sulfhidrilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.5.1.65 | ||||||||
| CAS broj | 1071505-11-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- O-fosfo-L-serin + vodonik sulfid L-cistein + fosfat
Ovaj enzim je piridoksal-fosfatni protein. Enzim iz Aeropyrum pernix deluje O-fosfo-L-serin i O3-acetil-L-serin, za razliku od enzima EC 2.5.1.47, cistein sintaze, koji deluje samo na O3-acetil-L-serin.
Reference уреди
- ^ Mino, K. & Ishikawa, K. (2003). „A novel O-phospho-L-serine sulfhydrylation reaction catalyzed by O-acetylserine sulfhydrylase from Aeropyrum pernix K1”. FEBS Lett. 551: 133—138. PMID 12965218.
- ^ Mino, K. & Ishikawa, K. (2003). „Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1”. J. Bacteriol. 185: 2277—2284. PMID 12644499.
- ^ Mino, K. & Ishikawa, K. (2003). „Crystallization and preliminary X-ray diffraction analysis of O-acetylserine sulfhydrylase from Aeropyrum pernix K1”. Acta Crystallogr. D Biol. Crystallogr. 59: 338—340. PMID 12554945.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- O-phosphoserine+sulfhydrylase на US National Library of Medicine Medical Subject Headings (MeSH)
