Pektatna lijaza
Pektatna lijaza (EC 4.2.2.2, poligalakturonska transeliminaza, pektinsko kiselinska transeliminaza, poligalakturonatna lijaza, endopektinska metiltranseliminaza, pektatna transeliminaza, endogalakturonatna transeliminaua, pektinsko kiselinska lijaza, alfa-1,4-D-endopoligalakturonsko kiselinska lijaza, PGA lijaza, PPase-N, endo-alfa-1,4-poligalakturonsko kiselinska lijaza, poligalakturonsko kiselinska lijaza, pektinska trans-eliminaza, poligalakturonsko kiselinska trans-eliminaza) je enzim sa sistematskim imenom (1->4)-alfa-D-galakturonan lijaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Pektatna lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.2.2 | ||||||||
| CAS broj | 9015-75-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Eliminativno razlaganje (1->4)-alfa-D-galakturonana kojim se formiraju oligosaharidi sa 4-dezoksi-alfa-D-galakt-4-enuronozil grupama na njihovim neredukujućim krajevima
Enzim je reaktivniji na pektatu, u odnosu na pektin.
Reference уреди
- ^ Albersheim, P. & Killias, U. (1962). „Studies relating to the purification and properties of pectin transeliminase”. Arch. Biochem. Biophys. 97: 107—115. PMID 13860094.
- ^ Edstrom, R.D. & Phaff, H.J. (1964). „Purification and certain properties of pectin trans-eliminase from Aspergillus fonsecaeus”. J. Biol. Chem. 239: 2403—2408. PMID 14235514.
- ^ Edstrom, R.D. & Phaff, H.J. (1964). „Eliminative cleavage of pectin and of oligogalacturonide methyl esters by pectin trans-eliminase”. J. Biol. Chem. 239: 2409—2415. PMID 14235515.
- ^ Nagel, C.W. & Vaughn, R.H. (1961). „The degradation of oligogalacturonides by the polygalacturonase of Bacillus polymyxa”. Arch. Biochem. Biophys. 94: 328—328. PMID 13727438.
- ^ Nasuno, S. & Starr, M.P. (1967). „Polygalacturonic acid trans-eliminase of Xanthomonas campestris”. Biochem. J. 104: 178—185. PMID 6035509.
- ^ Mayans, O., Scott, M., Connerton, I., Gravesen, T., Benen, J., Visser, J., Pickersgill, R. and Jenkins, J. (1997). „Two crystal structures of pectin lyase A from Aspergillus reveal a pH driven conformational change and striking divergence in the substrate-binding clefts of pectin and pectate lyases”. Structure. 5: 677—689. PMID 9195887.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Pectate+lyase на US National Library of Medicine Medical Subject Headings (MeSH)
