Piridoksalna fosfataza
Piridoksalna fosfataza (EC 3.1.3.74, vitamin B6 (piridoksin) fosfataza, PLP fosfataza, vitamin B6-fosfatna fosfataza, PNP fosfataza) je enzim sa sistematskim imenom piridoksal-5'-fosfat fosfohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Piridoksalna fosfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.3.74 | ||||||||
| CAS broj | 9076-92-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- piridoksal 5'-fosfat + H2O piridoksal + fosfat
Za rad ovog enzim je neophodan Mg2+.
Reference уреди
- ^ Fonda, M.L. (1992). „Purification and characterization of vitamin B6-phosphate phosphatase from human erythrocytes”. J. Biol. Chem. 267: 15978—15983. PMID 1322411.
- ^ Fonda, M.L. & Zhang, Y.N. (1995). „Kinetic mechanism and divalent metal activation of human erythrocyte pyridoxal phosphatase”. Arch. Biochem. Biophys. 320: 345—352. PMID 7625842.
- ^ Jang, Y.M., Kim, D.W., Kang, T.C., Won, M.H., Baek, N.I., Moon, B.J., Choi, S.Y. and Kwon, O.S. (2003). „Human pyridoxal phosphatase. Molecular cloning, functional expression, and tissue distribution”. J. Biol. Chem. 278: 50040—50046. PMID 14522954.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Pyridoxal+phosphatase на US National Library of Medicine Medical Subject Headings (MeSH)
