Prefenatna dehidrataza
Prefenatna dehidrataza (EC 4.2.1.51, prefenatna hidrolijaza (dekarboksilacija)) je enzim sa sistematskim imenom prefenat hidrolijaza (dekarboksilacija; formira fenilpiruvat).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Prefenatna dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.51 | ||||||||
| CAS broj | 9044-88-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- prefenat fenilpiruvat + H2O + CO2
Bakterijski enzim takođe deluje kao horizmat mutaza (EC 5.4.99.5).
Reference уреди
- ^ Cerutti, P. & Guroff, G. (1965). „Enzymatic formation of phenylpyruvic acid in Pseudomonas sp. (ATCC 11299A) and its regulation”. J. Biol. Chem. 240: 3034—3048. PMID 14342329.
- ^ Cotton, R.G.H. & Gibson, F. (1965). „The biosynthesis of phenylalanine and tyrosine; enzymes converting chorismic acid into prephenic acid and their relationships to prephenate dehydratase and prephenate dehydrogenase”. Biochim. Biophys. Acta. 100: 76—88. PMID 14323651.
- ^ Schmidt, J.C. & Zalkin, H. (1969). „Chorismate mutase-prephenate dehydratase. Partial purification and properties of the enzyme from Salmonella typhimurium”. Biochemistry. 8: 174—181.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Prephenate+dehydratase на US National Library of Medicine Medical Subject Headings (MeSH)
