Propandiolna dehidrataza
Propandiolna dehidrataza (EC 4.2.1.28, meso-2,3-butandiol dehidraza, diolna dehidrataza, DL-1,2-propandiol hidrolijaza, diolna dehidraza, adenozilkobalamin-zavisna diolna dehidrataza, propandiolna dehidraza, koenzim B12-zavisna diolna dehidraza, 1,2-propandiolna dehidrataza, dioldehidrataza, propan-1,2-diolna hidrolijaza) je enzim sa sistematskim imenom propan-1,2-diol hidrolijaza (formira propanal).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Propandiolna dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.28 | ||||||||
| CAS broj | 9026-90-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- propan-1,2-diol propanal + H2O
Za dejstvo ovog enzima je neophodan kobamidni koenzim.
Reference уреди
- ^ Abeles, R.H. & Lee, H.A., Jr. (1961). „An intramolecular oxidation-reduction requiring a cobamide coenzyme”. J. Biol. Chem. 236: 2347—2350. PMID 13680987.
- ^ Forage, R.G. & Foster, M.A. (1982). „Glycerol fermentation in Klebsiella pneumoniae: functions of the coenzyme B12-dependent glycerol and diol dehydratases”. J. Bacteriol. 149: 413—419. PMID 7035429.
- ^ Lee, H.A. & Abeles, R.H. (1963). „Purification and properties of dioldehydrase, and enzyme requiring a cobamide coenzyme”. J. Biol. Chem. 238: 2367—2373. PMID 13929077.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Propanediol+dehydratase на US National Library of Medicine Medical Subject Headings (MeSH)
