Riboza-fosfat difosfokinaza
Riboza-fosfat difosfokinaza (EC 2.7.6.1, riboza-fosfatna pirofosfokinaza, PRPP sintetaza, fosforibozilpirofosfatna sintetaza, PPRibP sintetaza, PP-riboza P sintetaza, 5-fosforibozil-1-pirofosfatna sintetaza, 5-fosforibozna pirofosforilaza, 5-fosforibozil-alfa-1-pirofosfatna sintetaza, fosforibozil-difosfatna sintetaza, fosforibozilpirofosfatna sintaza, pirofosforibozilfosfatna sintetaza, ribofosfatna pirofosfokinaza, riboza-5-fosfatna pirofosfokinaza) je enzim sa sistematskim imenom ATP:D-riboza-5-fosfat difosfotransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
Riboza-fosfat difosfokinaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.7.6.1 | ||||||||
CAS broj | 9015-83-2 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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dATP takođe može da deluje kao donor.
Reference
уреди- ^ Hughes, D.E. & Williamson, D.H. (1952). „Some properties of glutaminase of Clostridium welchii”. Biochem. J. 51: 45—55. PMID 14944530.
- ^ Hurlbert, R.B. & Reichard, P. (1955). „The conversion of orotic acid to uridine nucleotides in vitro”. Acta Chem. Scand. 9: 251—262.
- ^ Remy, C.N., Remy, W.T. and Buchanan, J.M. (1955). „Biosynthesis of the purines. VIII. Enzymatic synthesis and utilization of α-5-phosphoribosylpyrophosphate”. J. Biol. Chem. 217: 885—895. PMID 13271449.
- ^ Switzer, R.L. (1969). „Regulation and mechanism of phosphoribosylpyrophosphate synthetase. I. Purification and properties of the enzyme from Salmonella typhimurium”. J. Biol. Chem. 244: 2854—2863. PMID 4306285.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Ribose-phosphate+diphosphokinase на US National Library of Medicine Medical Subject Headings (MeSH)