Rubredoksin—NAD+ reduktaza
Rubredoksin—NAD+ reduktaza (EC 1.18.1.1, rubredoksinska reduktaza, rubredoksin-nikotinamid adenin dinukleotidna reduktaza, dihidronikotinamid adenin dinukleotid-rubredoksinska reduktaza, redukovani nikotinamid adenin dinukleotid-rubredoksinska reduktaza, NADH-rubredoksinska reduktaza, rubredoksin-NAD reduktaza, NADH: rubredoksinska oksidoreduktaza, DPNH-rubredoksinska reduktaza, NADH-rubredoksinska oksidoreduktaza) je enzim sa sistematskim imenom rubredoksin:NAD+ oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Rubredoksin—NAD+ reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.18.1.1 | ||||||||
| CAS broj | 9032-27-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 2 redukovani rubredoksin + NAD+ + H+ 2 oksidovani rubredoksin + NADH
Za rad ovog enzima je neophodan FAD. Enzim iz Clostridium acetobutilicum redukuje rubredoksin, fericijanid i dihlorofenolindofenol.
Reference уреди
- ^ Peterson, J.A., Kusunose, M., Kusunose, E. and Coon, M.J. (1967). „Enzymatic ω-oxidation. II. Function of rubredoxin as the electron carrier in ω-hydroxylation”. J. Biol. Chem. 242: 4334—4340. PMID 4294330.
- ^ Ueda, T., Lode, E.T. and Coon, M.J. (1972). „Enzymatic ω-oxidation. VI. Isolation of homogeneous reduced diphosphopyridine nucleotide-rubredoxin reductase”. J. Biol. Chem. 247: 2109—2116. PMID 4335861.
- ^ Ueda, T., Lode, E.T. and Coon, M.J. (1972). „Enzymatic oxidation. VII. Reduced diphosphopyridine nucleotide-rubredoxin reductase: properties and function as an electron carrier in hydroxylation”. J. Biol. Chem. 247: 5010—5016. PMID 4403503.
- ^ Petitdemange, H., Marczak, R., Blusson, H. and Gay, R. (1979). „Isolation and properties of reduced nicotinamide adenine dinucleotide rubredoxin oxidoreductase of Clostridium acetobutylicum”. Biochem. Biophys. Res. Commun. 91: 1258—1265. PMID 526302.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Rubredoxin—NAD+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
