Selenat reduktaza
Selenat reduktaza (EC 1.97.1.9, Selenate reductase) je enzim sa sistematskim imenom selenit:redukovani akceptor oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju:
| Selenat reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.97.1.9 | ||||||||
| CAS broj | 146359-71-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- selenit + H2O + akceptor selenat + redukovani akceptor
Periplazmički enzim iz Thauera selenatis je kompleks koji se sastoji od tri heterologne podjednice (alfa, beta i gama). On sadrži molibden, gvožđe, sulfid i hem B kao kofaktorske konstituente. Nitrat, nitrit, hlorat i sulfat su supstrati.
Reference уреди
- ^ Schröder, I., Rech, S., Krafft, T. and Macy, J.M. (1997). „Purification and characterization of the selenate reductase from Thauera selenatis”. J. Biol. Chem. 272: 23765—23768. PMID 9295321.
- ^ Macy, J.M., Rech, S., Auling, G., Dorsch, M., Stackebrandt, E. and Sly, L.I. (1993). „Thauera selenatis gen. nov., sp. nov., a member of the β subclass of Proteobacteria with a novel type of anaerobic respiration”. Int. J. Syst. Bacteriol. 43: 135—142. PMID 8427805.
- ^ Krafft, T., Bowen, A., Theis, F. and Macy, J.M. (2000). „Cloning and sequencing of the genes encoding the periplasmic-cytochrome B-containing selenate reductase of Thauera selenatis”. DNA. 10: 365—377. PMID 10826693.
- ^ Stolz, J.F. & Oremland, R.S. (1999). „Bacterial respiration of arsenic and selenium”. FEMS Microbiol. Rev. 23: 615—627. PMID 10525169.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Selenate+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
