Serin C-palmitoiltransferaza
Serin C-palmitoiltransferaza (EC 2.3.1.50, serinska palmitoiltransferaza, SPT, 3-oksosfinganinska sintetaza, acil-KoA:serin C-2 aciltransferaza dekarboksilacija) je enzim sa sistematskim imenom palmitoil-KoA:L-serin C-palmitoiltransferaza (dekarboksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Serin C-palmitoiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.50 | ||||||||
| CAS broj | 62213-50-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- palmitoil-KoA + L-serin KoA + 3-dehidro-D-sfinganin + CO2
Ovaj enzim je piridoksal-fosfatni protein.
Reference уреди
- ^ Brady, R.N., DiMari, S.J. and Snell, E.E. (1969). „Biosynthesis of sphingolipid bases. 3. Isolation and characterization of ketonic intermediates in the synthesis of sphingosine and dihydrosphingosine by cell-free extracts of Hansenula ciferri”. J. Biol. Chem. 244: 491—496. PMID 4388074.
- ^ Stoffel, W., Le Kim, D. and Sticht, G. (1968). „Biosynthesis of dihydrosphingosine in vitro”. Hoppe-Seyler's Z. Physiol. Chem. 349: 664—670. PMID 4386961.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Serine+C-palmitoyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
