Sorbozna reduktaza
Sorbozna reduktaza (EC 1.1.1.289, Sou1p) je enzim sa sistematskim imenom D-glucitol:NADP+ oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Sorbozna reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.289 | ||||||||
| CAS broj | 138440-90-1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- D-glucitol + NADP+ L-sorboza + NADPH + H+
Reakcija se predominantno odvija u reverznom smeru. Ovaj enzim takođe može da konvertuje D-fruktozu u D-manitol, ali sa manjom brzinom. Sorbozna reduktaza pripada familiji dehidrogenaza kratkog lanca.
Reference
уреди- ^ Greenberg, J.R., Price, N.P., Oliver, R.P., Sherman, F. and Rustchenko, E. (2005). „Candida albicans SOU1 encodes a sorbose reductase required for L-sorbose utilization”. Yeast. 22: 957—969. PMID 16134116.
- ^ Greenberg, J.R., Price, N.P., Oliver, R.P., Sherman, F. and Rustchenko, E. (2005). „Erratum report: Candida albicans SOU1 encodes a sorbose reductase required for L-sorbose utilization”. Yeast. 22: 1171—1171.
- ^ Sugisawa, T., Hoshino, T. and Fujiwara, A. (1991). „Purification and properties of NADPH-linked L-sorbose reductase from Gluconobacter melanogenus N44-1”. Agric. Biol. Chem. 55: 2043—2049.
- ^ Shinjoh, M., Tazoe, M. and Hoshino, T. (2002). „NADPH-dependent L-sorbose reductase is responsible for L-sorbose assimilation in Gluconobacter suboxydans IFO 3291”. J. Bacteriol. 184: 861—863. PMID 11790761.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Sorbose+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
