Spermidin dehidrogenaza
Spermidin dehidrogenaza (EC 1.5.99.6, spermidin:(akceptor) oksidoreduktaza) je enzim sa sistematskim imenom spermidin:akceptor oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju:
| Spermidin dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.99.6 | ||||||||
| CAS broj | 9076-64-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- spermidin + akceptor + H2O propan-1,3-diamin + 4-aminobutanal + redukovani akceptor
Ovaj enzim je flavohemoprotein (FAD). Fericijanid, 2,6-dihloroindofenol i citohrom c mogu da budu akceptori.
Reference уреди
- ^ Tabor, C.W. & Kellogg, P.D. (1970). „Identification of flavin adenine dinucleotide and heme in a homogeneous spermidine dehydrogenase from Serratia marcescens”. J. Biol. Chem. 245: 5424—5433. PMID 4918845.
- ^ Tabor, H. & Tabor, C.W. (1972). „Biosynthesis and metabolism of 1,4-diaminobutane, spermidine, spermine, and related amines. IIE2a Speridine dehydrogenase”. Adv. Enzymol. Relat. Areas Mol. Biol. 36: 225—226.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Spermidine+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
