Sumpor nosilac protein ThiS adenililtransferaza
Sumpor nosilac protein ThiS adenililtransferaza (EC 2.7.7.73, thiF (gen)) je enzim sa sistematskim imenom ATP:(ThiS) adenililtransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
Sumpor nosilac protein ThiS adenililtransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.7.7.73 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
|
- ATP + [ThiS] difosfat + adenilil-[ThiS]
Ovaj enzim vezuje jon Zn2+.
Reference
уреди- ^ Taylor, S.V., Kelleher, N.L., Kinsland, C., Chiu, H.J., Costello, C.A., Backstrom, A.D., McLafferty, F.W. and Begley, T.P. (1998). „Thiamin biosynthesis in Escherichia coli. Identification of this thiocarboxylate as the immediate sulfur donor in the thiazole formation”. J. Biol. Chem. 273: 16555—16560. PMID 9632726.
- ^ Xi, J., Ge, Y., Kinsland, C., McLafferty, F.W. and Begley, T.P. (2001). „Biosynthesis of the thiazole moiety of thiamin in Escherichia coli: identification of an acyldisulfide-linked protein--protein conjugate that is functionally analogous to the ubiquitin/E1 complex”. Proc. Natl. Acad. Sci. USA. 98: 8513—8518. PMID 11438688.
- ^ Duda, D.M., Walden, H., Sfondouris, J. and Schulman, B.A. (2005). „Structural analysis of Escherichia coli ThiF”. J. Mol. Biol. 349: 774—786. PMID 15896804.
- ^ Lehmann, C., Begley, T.P. and Ealick, S.E. (2006). „Structure of the Escherichia coli ThiS-ThiF complex, a key component of the sulfur transfer system in thiamin biosynthesis”. Biochemistry. 45: 11—19. PMID 16388576.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Sulfur+carrier+protein+ThiS+adenylyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)