Terpentedienil-difosfatna sintaza
Terpentedienil-difosfatna sintaza (EC 5.5.1.15, terpentedienol difosfatna sintaza, Cyc1, klerodadienil difosfatna sintaza) je enzim sa sistematskim imenom terpentedienil-difosfat lijaza (deciklizacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Terpentedienil-difosfatna sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.5.1.15 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- geranilgeranil difosfat terpentedienil difosfat
Za dejstvo ovog enzima je neophodan jon Mn2+.
Reference
уреди- ^ Dairi, T., Hamano, Y., Kuzuyama, T., Itoh, N., Furihata, K. and Seto, H. (2001). „Eubacterial diterpene cyclase genes essential for production of the isoprenoid antibiotic terpentecin”. J. Bacteriol. 183: 6085—6094. PMID 11567009.
- ^ Hamano, Y., Kuzuyama, T., Itoh, N., Furihata, K., Seto, H. and Dairi, T. (2002). „Functional analysis of eubacterial diterpene cyclases responsible for biosynthesis of a diterpene antibiotic, terpentecin”. J. Biol. Chem. 277: 37098—37104. PMID 12138123.
- ^ Eguchi, T., Dekishima, Y., Hamano, Y., Dairi, T., Seto, H. and Kakinuma, K. (2003). „A new approach for the investigation of isoprenoid biosynthesis featuring pathway switching, deuterium hyperlabeling, and 1H NMR spectroscopy. The reaction mechanism of a novel streptomyces diterpene cyclase”. J. Org. Chem. 68: 5433—5438. PMID 12839434.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Terpentedienyl-diphosphate+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
