Tetrahimanolna sintaza
Tetrahimanolna sintaza (EC 4.2.1.123, skvalen tetrahimanolna ciklaza) je enzim sa sistematskim imenom skvalen hidrolijaza (formira tetrahimanol).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Tetrahimanolna sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.123 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- tetrahimanol skvalen + H2O
Ova reakcija se odvija u reverznom smeru.
Reference уреди
- ^ Saar, J., Kader, J.C., Poralla, K. and Ourisson, G. (1991). „Purification and some properties of the squalene-tetrahymanol cyclase from Tetrahymena thermophila”. Biochim. Biophys. Acta. 1075: 93—101. PMID 1892870.
- ^ Giner, J.L., Rocchetti, S., Neunlist, S., Rohmer, M. and Arigoni, D. (2005). „Detection of 1,2-hydride shifts in the formation of euph-7-ene by the squalene-tetrahymanol cyclase of Tetrahymena pyriformis”. Chem. Commun. (Camb.): 3089—3091. PMID 15959594.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Tetrahymanol+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
