Tetrahloroeten reduktivna dehalogenaza
Tetrahloroeten reduktivna dehalogenaza (EC 1.97.1.8, tetrahloroeten reduktaza) je enzim sa sistematskim imenom akceptor:trihloroeten oksidoreduktaza (hlorinacija).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju:
| Tetrahloroeten reduktivna dehalogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.97.1.8 | ||||||||
| CAS broj | 163913-51-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- trihloroeten + hlorid + akceptor tetrahloroeten + redukovani akceptor
Ovaj enzim omogućava zagađivaču tetrahloroetenu da podržava bakterijski rast i odgovoran je za uklanjanje brojnih hlorinisanih ugljovodonika posredstvom tog organizma.
Reference уреди
- ^ Holliger, C, Wohlfarth, G. and Diekert, G. (1998). „Reductive dechlorination in the energy metabolism of anaerobic bacteria”. FEMS Microbiol. Rev. 22: 383—398.
- ^ Glod, G., Angst, W., Holliger, C. and Schwarzenbach, R.P. (1997). „Corrinoid-mediated reduction of tetrachloroethene, trichloroethene, and trichlorofluoroethene in homogeneous aqueous solution: Reaction kinetics and reaction mechanisms”. Environ. Sci. Technol. 31: 253—260.
- ^ Neumann, A., Wohlfarth, G. and Diekert, G. (1996). „Purification and characterization of tetrachloroethene reductive dehalogenase from Dehalospirillum multivorans”. J. Biol. Chem. 271: 16515—16519. PMID 8663199.
- ^ Schumacher, W., Holliger, C., Zehnder, A.J.B. and Hagen, W.R. (1997). „Redox chemistry of cobalamin and iron-sulfur cofactors in the tetrachloroethene reductase of Dehalobacter restrictus”. FEBS Lett. 409: 421—425. PMID 9224702.
- ^ Schumacher, W. & Holliger, C. (1996). „T'he proton/electron ratio of the menaquinone-dependent electron transport from dihydrogen to tetrachloroethene in "Dehalobacter restrictus"”. J. Bacteriol. 178: 2328—2333. PMID 8636034.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Tetrachloroethene+reductive+dehalogenase на US National Library of Medicine Medical Subject Headings (MeSH)
