Thermospermin sintaza
Thermospermin sintaza (EC 2.5.1.79, TSPMS, ACL5, SAC51) je enzim sa sistematskim imenom S-adenozilmetioninamin:spermidin 3-aminopropiltransferaza (termospermin sinteza).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Thermospermin sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.5.1.79 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- S-adenozilmetioninamin + spermidin S-metil-5'-tioadenozin + termospermin + H+
Ovaj enzim je neophodan za korektnu specifikaciju ksilema, što se ostvaruje putem regulacije životnog veka ksilemskih elemenata.
Reference
уреди- ^ Romer, P., Faltermeier, A., Mertins, V., Gedrange, T., Mai, R. and Proff, P. (2008). „Investigations about N-aminopropyl transferases probably involved in biomineralization”. J. Physiol. Pharmacol. 59 Suppl 5: 27—37. PMID 19075322.
- ^ Knott, J.M., Romer, P. and Sumper, M. (2007). „Putative spermine synthases from Thalassiosira pseudonana and Arabidopsis thaliana synthesize thermospermine rather than spermine”. FEBS Lett. 581: 3081—3086. PMID 17560575.
- ^ Muniz, L., Minguet, E.G., Singh, S.K., Pesquet, E., Vera-Sirera, F., Moreau-Courtois, C.L., Carbonell, J., Blazquez, M.A. and Tuominen, H. (2008). „ACAULIS5 controls Arabidopsis xylem specification through the prevention of premature cell death”. Development. 135: 2573—2582. PMID 18599510.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Thermospermine+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
