Tiamin piridinilaza
Tiamin piridinilaza (EC 2.5.1.2, pirimidinska transferaza, tiaminaza I, tiaminska hidrolaza, tiaminska piridinolaza, tiaminska piridinolaza, tiaminska piridinilaza, tiamin:baza 2-metil-4-aminopirimidin-5-meteniltransferaza) je enzim sa sistematskim imenom tiamin:base 2-metil-4-aminopirimidin-5-meteniltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Tiamin piridinilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.5.1.2 | ||||||||
| CAS broj | 9030-35-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- tiamin + piridin 1-[(4-amino-2-metilpirimidin-5-il)metil]piridinijum + 4-metil-5-(2-hidroksietil)tiazol
Razna bazna i tiolna jedinjenja mogu da deluju umesto piridina.
Reference уреди
- ^ Fujita, A. (1954). „Thiaminases”. Adv. Enzymol. Relat. Subj. Biochem. 15: 389—421. PMID 13158184.
- ^ Kenten, R.H. (1957). „The partial purification and properties of a thiaminase from bracken [Pteridium aquilinum (L.) Kuhn]”. Biochem. J. 67: 25—33. PMID 13471505.
- ^ Wittliff, J.L. & Airth, R.L. (1968). „The extracellular thiaminase I of Bacillus thiaminolyticus. I. Purification and physicochemical properties”. Biochemistry. 7: 736—744. PMID 4966932.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Thiamine+pyridinylase на US National Library of Medicine Medical Subject Headings (MeSH)
