Togavirin

Togavirin (EC 3.4.21.90, Sindbis virus proteaza, Sindbis virus core protein, NsP2 proteinaza) je enzim.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Togavirin

Identifikatori

Baze podataka

NiceZyme pregled

metabolički put

Strukture PBP

RCSB PDB PDBe PDBj PDBsum

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Autokatalitičko odvajanje sržnog proteina sa N-terminusa togavirusnog strukturnog poliproteina putem hidrolize -Trp-Ser- veze

Ovaj enzim kodiraju Sindbis i Semliki šumski togavirusi.

Reference

^ Kräusslich, H.-G. and Wimmer, E. (1988). „Viral proteinases”. Annu. Rev. Biochem. 57: 701—754. PMID 3052288.
^ Strauss, E.G., De Groot, R.J., Levinson, R. and Strauss, J.H. (1992). „Identification of the active site residues in the nsP2 proteinase of Sindbis virus”. Virology. 191: 932—940. PMID 1448929.
^ Tong, L., Wengler, G. and Rossmann, M.G. (1993). „Refined structure of Sindbis virus core protein and comparison with other chymotrypsin-like serine proteinase structures”. J. Mol. Biol. 230: 228—247. PMID 8450538.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Togavirin на US National Library of Medicine Medical Subject Headings (MeSH)

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