Trimerlizin II
Trimerlizin II (EC 3.4.24.53, Trimeresurus metaloendopeptidaza II, proteinaza H2, H2-proteinaza) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Trimerlizin II | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.53 | ||||||||
| CAS broj | 151125-15-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Razlaganje Asn3-Gln, His10-Leu i Ala14-Leu u lancu insulina B, i veze Z-Gly-Pro-Leu-Gly-Pro malim molekulima koji su supstrati mikrobne kolagenaze
Ova nehemoragična endopeptidaza je prisutna u venumu zmije Trimeresurus flavoviridis.
Reference
уреди- ^ Takahashi, T. & Ohsaka, A. (1970). „Purification and characterization of a proteinase in the venom of Trimeresurus flavoviridis. Complete separation of the enzyme from hemorrhagic activity”. Biochim. Biophys. Acta. 198: 293—307. PMID 4984550.
- ^ Takeya, H., Arakawa, M., Miyata, T., Iwanaga, S. and Omori-Satoh, T. (1989). „Primary structure of H2-proteinase, a non-hemorrhagic metalloproteinase, isolated from the venom of the habu snake, Trimeresurus flavoviridis”. J. Biochem. (Tokyo). 106: 151—157. PMID 2777746.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Trimerelysin+II на US National Library of Medicine Medical Subject Headings (MeSH)
