UDP-N-acetilgalaktozamin difosforilaza
UDP-N-acetilgalaktozamin difosforilaza (EC 2.7.7.83, UDP-N-acetylgalactosamine diphosphorylase) je enzim sa sistematskim imenom UTP:N-acetil-alfa-D-galaktozamin-1-fosfat uridililtransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| UDP-N-acetilgalaktozamin difosforilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.7.83 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- UTP + N-acetil-alfa-D-galaktozamin 1-fosfat difosfat + UDP-N-acetil-alfa-D-galaktozamin
Enzim biljki i životinja takođe deluje na N-acetil-alfa-D-glukozamin 1-fosfat.
Reference уреди
- ^ Wang-Gillam, A., Pastuszak, I. and Elbein, A.D. (1998). „A 17-amino acid insert changes UDP-N-acetylhexosamine pyrophosphorylase specificity from UDP-GalNAc to UDP-GlcNAc”. J. Biol. Chem. 273: 27055—27057. PMID 9765219.
- ^ Peneff, C., Ferrari, P., Charrier, V., Taburet, Y., Monnier, C., Zamboni, V., Winter, J., Harnois, M., Fassy, F. and Bourne, Y. (2001). „Crystal structures of two human pyrophosphorylase isoforms in complexes with UDPGlc(Gal)NAc: role of the alternatively spliced insert in the enzyme oligomeric assembly and active site architecture”. EMBO J. 20: 6191—6202. PMID 11707391.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- UDP-N-acetylgalactosamine+diphosphorylase на US National Library of Medicine Medical Subject Headings (MeSH)
