UDP-N-acetilmuramoilalanil-D-glutamat-2,6-diamino-pimelatna ligaza
(преусмерено са UDP-N-acetilmuramoilalanil-D-glutamat-2,6-diamino-pimelat ligaza)
UDP-N-acetilmuramoilalanil-D-glutamat-2,6-diamino-pimelatna ligaza (EC 6.3.2.13, MurE sintetaza, UDP-N-acetilmuramoil-L-alanil-D-glutamat:meso-2,6-diamino-heptanedioat ligaza (formira ADP), UDP-N-acetilmuramoil-L-alanil-D-glutamil-meso-2,6-diaminopimelat sintetaza, UDP-N-acetilmuramoilalanil-D-glutamat—2,6-diaminopimelat ligaza) je enzim sa sistematskim imenom UDP-N-acetilmuramoil-L-alanil-D-glutamat:meso-2,6-diaminoheptandioat gama-ligaza (formira ADP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| UDP-N-acetilmuramoilalanil-D-glutamat-2,6-diamino-pimelatna ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.3.2.13 | ||||||||
| CAS broj | 2620865 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- ATP + UDP-N-acetilmuramoil-L-alanil-D-glutamat + meso-2,6-diaminoheptanedioat ADP + fosfat + UDP-N-acetilmuramoil-L-alanil-D-gama-glutamil-meso-2,6-diaminoheptanedioat
Ovaj enzim učestvuje u sintezi peptida ćelijskog zida.
Reference уреди
- ^ Mizuno, Y. & Ito, E. (1968). „Purification and properties of uridine diphosphate N-acetylmuramyl-L-alanyl-D-glutamate:meso-2,6-diaminopimelate ligase”. J. Biol. Chem. 243: 2665—2672. PMID 4967958.
- ^ van Heijenoort, J. (2001). „Recent advances in the formation of the bacterial peptidoglycan monomer unit”. Nat. Prod. Rep. 18: 503—519. PMID 11699883.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---2,6-diaminopimelate+ligase на US National Library of Medicine Medical Subject Headings (MeSH)
