Vakcenska kiselina

Vakcenska kiselina
Nazivi
	IUPAC naziv (E)-Oktadek-11-enoinska kiselina
Identifikacija
CAS broj	693-72-1 ;
3D model (Jmol)	interaktivna slika;
ChEBI	CHEBI:28727 ;
ChemSpider	4444571 ;
ECHA InfoCard	100.010.691
PubChem C ID	5281127;
	SMILES CCCCCC/C=C/CCCCCCCCCC(O)=O; ; ; ; ; ;
Svojstva
Hemijska formula	C18H34O2
Molarna masa	282,461 g/mol
	Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
	verifikuj (šta je ?)
	Reference infokutije

Vakcenska kiselina je omega-7 masna kiselina. Ona je prirodna trans-masna kiselina prisutna u masti ruminirajućih životinja i mlečnim proizvodima (mleku, puteru, i jogurtu).^[3] On je takođe predominantna masna kiselina u ljudskom mleku.^[4]^[5]

Njeno IUPAC ime je (E)-11-oktadecenoinska kiselina, a njeno lipidno skraćeno ime je 18:1 trans-11. Ime je izvedeno iz lat. vacca - krava.^[6]

Vakcenska kiselina je otrkivena 1928 u životinjskim mastima i puteru. Ona je glavni 'trans-masno kiselinski izomer prisutan u mlečnoj masti.^[6] Sisari je konvertuju u rumensku kiselinu, konjugovanju linoleinsku kiselinu,^[7]^[8] koja ima antikarcinogena svojstva.^[9]

Reference уреди

^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. уреди
^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
^ Natural trans fats may be good for you. May 19, 2008
^ Precht, D and J.Molkentin C18:1, C18:2, and C8:3 trans and cis fatty acid isomers including conjugated cis delta 9, trans delta 11 linoleic acid (CLA) as well as total fat composition of German human milk lipids, Nahrung 1999 43(4) 233-244
^ Friesen, R, and S.M. Innis, Trans Fatty acids in Human milk in Canada declined with the introduction of trans fat food labeling, J. Nut 2006, 136 2558-2561
^ ^а ^б F. Destaillats, E. Buyukpamukcu, P.-A. Golay, F. Dionisi and F. Giuffrida (2005). „Letter to the Editor: Vaccenic and Rumenic Acids, A Distinct Feature of Ruminant Fats”. J. Dairy Sci. 88 (449).
^ Bauman, Dale. „cis-9, trans-11 CLA - A Potent Anticarcinogen Found in Milk Fat”. Архивирано из оригинала 07. 09. 2006. г. Приступљено 15. 01. 2007.
^ Banni S, Angioni E, Murru E, Carta G, Melis M, Bauman D, Dong Y, Ip C (2001). „Vaccenic acid feeding increases tissue levels of conjugated linoleic acid and suppresses development of premalignant lesions in rat mammary gland”. Nutr Cancer. 41 (1-2): 91—7. PMID 12094634. doi:10.1207/S15327914NC41-1&2_12.
^ Lock AL, Corl BA, Barbano DM, Bauman DE, Ip C (1. 10. 2004). „The anticarcinogenic effect of trans-11 18:1 is dependent on its conversion to cis-9, trans-11 CLA by delta9-desaturase in rats”. J Nutr. 134 (10): 2698—704. PMID 15465769. Приступљено 15. 01. 2007.

Spoljašnje veze уреди

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. уреди

[2] Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.

[3] Natural trans fats may be good for you. May 19, 2008

[4] Precht, D and J.Molkentin C18:1, C18:2, and C8:3 trans and cis fatty acid isomers including conjugated cis delta 9, trans delta 11 linoleic acid (CLA) as well as total fat composition of German human milk lipids, Nahrung 1999 43(4) 233-244

[5] Friesen, R, and S.M. Innis, Trans Fatty acids in Human milk in Canada declined with the introduction of trans fat food labeling, J. Nut 2006, 136 2558-2561

[Destaillats-6] а ^б F. Destaillats, E. Buyukpamukcu, P.-A. Golay, F. Dionisi and F. Giuffrida (2005). „Letter to the Editor: Vaccenic and Rumenic Acids, A Distinct Feature of Ruminant Fats”. J. Dairy Sci. 88 (449).

[Bauman-7] Bauman, Dale. „cis-9, trans-11 CLA - A Potent Anticarcinogen Found in Milk Fat”. Архивирано из оригинала 07. 09. 2006. г. Приступљено 15. 01. 2007.

[Banni-8] Banni S, Angioni E, Murru E, Carta G, Melis M, Bauman D, Dong Y, Ip C (2001). „Vaccenic acid feeding increases tissue levels of conjugated linoleic acid and suppresses development of premalignant lesions in rat mammary gland”. Nutr Cancer. 41 (1-2): 91—7. PMID 12094634. doi:10.1207/S15327914NC41-1&2_12.

[lock-9] Lock AL, Corl BA, Barbano DM, Bauman DE, Ip C (1. 10. 2004). „The anticarcinogenic effect of trans-11 18:1 is dependent on its conversion to cis-9, trans-11 CLA by delta9-desaturase in rats”. J Nutr. 134 (10): 2698—704. PMID 15465769. Приступљено 15. 01. 2007.

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