Vibriolizin
Vibriolizin (EC 3.4.24.25, Aeromonas proteolytica neutralna proteinaza, aeromonolizin) je enzim.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Vibriolizin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.25 | ||||||||
| CAS broj | 69598-88-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Preferentno razlaganje veza sa glomaznim hidrofobnim grupama u P2 i P1'. Phe u P1' je preferentni ostatak, po čemu se ovaj enzim razlikuje od termolizina
Ovaj termostablni enzim je prisutan u Vibrio proteolyticus.
Reference
уреди- ^ Holmquist, B. & Vallee, B.L. (1976). „Esterase activity of zinc neutral proteases”. Biochemistry. 15: 101—107. PMID 2276.
- ^ Wilkes, S.H. & Prescott, J.M. (1976). „Aeromonas neutral protease”. Methods Enzymol. 45: 404—415. PMID 1012006.
- ^ Bayliss, M.E., Wilkes, S.H. and Prescott, J.M. (1980). „Aeromonas neutral protease: specificity toward extended substrates”. Arch. Biochem. Biophys. 204: 214—219. PMID 7000005.
- ^ Wilkes, S.H., Bayliss, M.E. and Prescott, J.M. (1988). „Critical ionizing groups in Aeromonas neutral protease”. J. Biol. Chem. 263: 1821—1825. PMID 3123480.
- ^ David, V.A., Deutch, A.H., Sloma, A., Pawlyk, D., Ally, A. and Durham, D.R. (1992). „Cloning, sequencing and expression of the gene encoding the extracellular neutral protease, vibriolysin, of Vibrio proteolyticus”. Gene. 112: 107—112. PMID 1551587.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Vibriolysin на US National Library of Medicine Medical Subject Headings (MeSH)
