Алдехид редуктаза
Aldehid reduktaza (EC 1.1.1.21, aldehidna reduktaza, aldoza reduktaza, poliol dehidrogenaza (NADP+), ALR2, alditol:NADP+ oksidoreduktaza, alditol:NADP+ 1-oksidoreduktaza, NADPH-aldopentoza reduktaza, NADPH-aldoza reduktaza) je enzim sa sistematskim imenom alditol:NAD(P)+ 1-oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Aldehid reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 1.1.1.21 | ||||||||
| CAS broj | 9028-31-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- alditol + NAD(P)+ aldoza + NAD(P)H + H+
Ima široku specifičnost.
Reference
уреди- ^ Attwood, M.A. & Doughty, C.C. (1974). „Purification and properties of calf liver aldose reductase”. Biochim. Biophys. Acta. 370: 358—368. PMID 4216364.
- ^ Boghosian, R.A. & McGuinness, E.T. (1979). „Affinity purification and properties of porcine brain aldose reductase”. Biochim. Biophys. Acta. 567: 278—286. PMID 36151.
- ^ Hers, H.G. (1960). „L’Aldose-réductase”. Biochim. Biophys. Acta. 37: 120—126. PMID 14401390.
- ^ Scher, B.M. & Horecker, B.L. (1966). „Pentose metabolism in Candida. 3. The triphosphopyridine nucleotide-specific polyol dehydrogenase of Candida utilis”. Arch. Biochem. Biophys. 116: 117—128. PMID 4381350.
Literatura
уреди- Ferrier, Denise R. (2005). Lippincott's Illustrated Reviews: Biochemistry (Lippincott's Illustrated Reviews). Hagerstown, Maryland: Lippincott Williams & Wilkins. стр. 319. ISBN 978-0-7817-2265-0.
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Aldehyde+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
