Бајикалин-бета-D-глукуронидаза
Baikalin-beta-D-glukuronidaza (EC 3.2.1.167, bajikalinaza) je enzim sa sistematskim imenom 5,6,7-trihidroksiflavon-7-O-beta-D-glukupiranoziduronatna glukuronazilhidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
Baikalin-beta-D-glukuronidaza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.2.1.167 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- bajikalin + H2O bajikalein + D-glukuronat
Ovaj enzim takođe u manjoj meri hidrolizuje vogonin 7-O-beta-D-glukuronid i oroksilin 7-O-beta-D-glukuronid.
Reference
уреди- ^ Ikegami, F., Matsunae, K., Hisamitsu, M., Kurihara, T., Yamamoto, T. and Murakoshi, I. (1995). „Purification and properties of a plant β-D-glucuronidase form Scutellaria root”. Biol. Pharm. Bull. 18: 1531—1534. PMID 8593473.
- ^ Zhang, C., Zhang, Y., Chen, J. and Liang, X. (2005). „Purification and characterization of baicalin-β-D-glucuronidase hydrolyzing baicalin to baicalein from fresh roots of Scutellaria viscidula Bge”. Proc. Biochem. 40: 1911—1915.
- ^ Sasaki, K., Taura, F., Shoyama, Y. and Morimoto, S. (2000). „Molecular characterization of a novel β-glucuronidase from Scutellaria baicalensis Georgi”. J. Biol. Chem. 275: 27466—27472. PMID 10858442.
- ^ Morimoto, S., Harioka, T. and Shoyama, Y. (1995). „Purification and characterization of flavone-specific β-glucuronidase from callus cultures of Scutellaria baicalensis Georgi”. Planta. 195: 535—540.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Baicalin-beta-D-glucuronidase на US National Library of Medicine Medical Subject Headings (MeSH)