D-аминокиселина оксидаза
D-aminokiselina oksidaza (EC 1.4.3.3, L-amino kiselina:O2 oksidoreduktaza) je enzim sa sistematskim imenom D-amino-kiselina:kiseonik oksidoreduktaza (deaminacija).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
D-aminokiselina oksidaza | |||||||||
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![]() 3D strukctur DAAO iz kvasca (monomer) | |||||||||
Identifikatori | |||||||||
EC broj | 1.4.3.3 | ||||||||
CAS broj | 9000-88-8 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- D-aminokiselina +H2O + O2 2-okso karboksilat + NH3 +H2O2
Ovaj enzim je flavoprotein (FAD). On ima široku specifičnost za D-aminokiseline. Takođe deluje na glicin.
Reference
уреди- ^ Dixon, M. & Kleppe, K. (1965). „D-Amino acid oxidase. I. Dissociation and recombination of the haloenzyme”. Biochim. Biophys. Acta. 96: 357—367. PMID 14314378.
- ^ Dixon, M. & Kleppe, K. (1965). „D-Amino acid oxidase. II. Specificity, competitive inhibition and reaction sequence”. Biochim. Biophys. Acta. 96: 368—382.
- ^ Dixon, M. & Kleppe, K. (1965). „D-Amino acid oxidase. III. Effect of pH”. Biochim. Biophys. Acta. 96: 383—389. PMID 14314379.
- ^ Massey, V., Palmer, G. and Bennett, R. (1961). „The purification and some properties of D-amino acid oxidase”. Biochim. Biophys. Acta. 48: 1—9. PMID 13767909.
- ^ Meister, A. & Wellner, D. (1963). „Flavoprotein amino acid oxidase”. Ур.: Boyer, P.D., Lardy, H.; Myrb; auml & ck, K. The Enzymes. 7 (2nd изд.). New York: Academic Press. стр. 609—648.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- D-amino-acid+oxidase на US National Library of Medicine Medical Subject Headings (MeSH)