Деметилменахинон метилтрансфераза
Demetilmenahinon metiltransferaza (EC 2.1.1.163, S-adenozil-L-metion---DMK metiltransferaza, demetilmenahinon C-metilaza, 2-heptaprenil-1,4-naftohinon metiltransferaza, 2-demetilmenahinon metiltransferaza, S-adenozil-L-metion:2-demetilmenahinon metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metion:demetilmenahinon metiltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Demetilmenahinon metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.163 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- demetilmenahinol + S-adenozil-L-metionin menahinol + S-adenozil-L-homocistein
Ovaj enzim katalizuje zadnji korak menahinonske biosinteza.
Reference
уреди- ^ Koike-Takeshita, A., Koyama, T. and Ogura, K. (1997). „Identification of a novel gene cluster participating in menaquinone (vitamin K2) biosynthesis. Cloning and sequence determination of the 2-heptaprenyl-1,4-naphthoquinone methyltransferase gene of Bacillus stearothermophilus”. J. Biol. Chem. 272: 12380—12383. PMID 9139683.
- ^ Wissenbach, U., Ternes, D. and Unden, G. (1992). „An Escherichia coli mutant containing only demethylmenaquinone, but no menaquinone: effects on fumarate, dimethylsulfoxide, trimethylamine N-oxide and nitrate respiration”. Arch. Microbiol. 158: 68—73. PMID 1444716.
- ^ Catala, F., Azerad, R. and Lederer, E. (1970). „Sur les propriétés de la desméthylménaquinone C-méthylase de Mycobacterium phlei”. Int. Z. Vitaminforsch. 40: 363—373. PMID 5450997.
- ^ Lee, P.T., Hsu, A.Y., Ha, H.T. and Clarke, C.F. (1997). „A C-methyltransferase involved in both ubiquinone and menaquinone biosynthesis: isolation and identification of the Escherichia coli ubiE gene”. J. Bacteriol. 179: 1748—1754. PMID 9045837.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Demethylmenaquinone+methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
