Карбамоил-фосфатна синтаза (амонијак)

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Karbamoil-fosfatna sintaza (amonijak)
Karbamoil-fosfatna sintaza (amonijak)
Identifikatori
EC broj	6.3.4.16
CAS broj	9026-23-7
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Karbamoil-fosfatna sintaza (amonijak) (EC 6.3.4.16, ugljen-dioksid—amonijak ligaza, karbamoilfosfatna sintaza, karbamilfosfatna sintetaza, karbamoilfosfatna sintaza (amonijak), karbamoilfosfatna sintetaza, karbamilfosfatna sintetaza I) je enzim sa sistematskim imenom ugljen-dioksid:amonijak ligaza (formira ADP, karbamatna fosforilacija).^[1]^[2]^[3]^[4] Ovaj enzim katalizuje sledeću hemijsku reakciju

2 ATP + NH₃ + CO₂ + H₂O

\rightleftharpoons

2 ADP + fosfat + karbamoil fosfat

Reference

^ Fahien, L.A. & Cohen, P.P. (1964). „A kinetic study of carbamyl phosphate synthetase”. J. Biol. Chem. 239: 1925—1934. PMID 14213379.
^ Jones, M.E. & Spector, L. (1960). „The pathway of carbonate in the biosynthesis of carbamyl phosphate”. J. Biol. Chem. 235: 2897—2901. PMID 13790558.
^ Marshall, M., Metzenberg, R.L. and Cohen, P.P. (1958). „Purification of carbamyl phosphate synthetase from frog liver”. J. Biol. Chem. 233: 102—105. PMID 13563449.
^ Marshall, M., Metzenberg, R.L. and Cohen, P.P. (1961). „Physical and kinetic properties of carbamyl phosphate synthetase from frog liver”. J. Biol. Chem. 236: 2229—2237.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Carbamoyl-phosphate+synthase+(ammonia) на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Fahien, L.A. & Cohen, P.P. (1964). „A kinetic study of carbamyl phosphate synthetase”. J. Biol. Chem. 239: 1925—1934. PMID 14213379.

[2] Jones, M.E. & Spector, L. (1960). „The pathway of carbonate in the biosynthesis of carbamyl phosphate”. J. Biol. Chem. 235: 2897—2901. PMID 13790558.

[3] Marshall, M., Metzenberg, R.L. and Cohen, P.P. (1958). „Purification of carbamyl phosphate synthetase from frog liver”. J. Biol. Chem. 233: 102—105. PMID 13563449.

[4] Marshall, M., Metzenberg, R.L. and Cohen, P.P. (1961). „Physical and kinetic properties of carbamyl phosphate synthetase from frog liver”. J. Biol. Chem. 236: 2229—2237.

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