Зн2+ експортујућа АТПаза
Zn2+ eksportujuća ATPaza (EC 3.6.3.5, Zn(II)-translocirajuća P-tip ATPaza, P1B-tip ATPaza, AtHMA4) je enzim sa sistematskim imenom ATP fosfohidrolaza (Zn2+ eksport).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Zn2+ eksportujuća ATPaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.6.3.5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ova P-tip ATPaza podleže kovalentnoj fosforilaciji tokom transportnog ciklusa.
Reference
уреди- ^ Beard, S.J., Hashim, R., Membrillo-Hernández, J., Hughes, M.N. and Poole, R.K. (1997). „Zinc(II) tolerance in Escherichia coli K-12: evidence that the zntA gene (o732) encodes a cation transport ATPase”. Mol. Microbiol. 25: 883—891. PMID 9364914.
- ^ Rensing, C., Mitra, B. and Rosen, B.P. (1997). „The zntA gene of Escherichia coli encodes a Zn(II)-translocating P-type ATPase”. Proc. Natl. Acad. Sci. USA. 94: 14326—14331. PMID 9405611.
- ^ Rensing, C., Sun, Y., Mitra, B. and Rosen, B.P. (1998). „Pb(II)-translocating P-type ATPases”. J. Biol. Chem. 273: 32614—32617. PMID 9830000.
- ^ Mills, R.F., Francini, A., Ferreira da Rocha, P.S., Baccarini, P.J., Aylett, M., Krijger, G.C. and Williams, L.E. (2005). „The plant P1B-type ATPase AtHMA4 transports Zn and Cd and plays a role in detoxification of transition metals supplied at elevated levels”. FEBS Lett. 579: 783—791. PMID 15670847.
- ^ Eren, E. & Argüello, J.M. (2004). „Arabidopsis HMA2, a divalent heavy metal-transporting P(IB)-type ATPase, is involved in cytoplasmic Zn2+ homeostasis”. Plant Physiol. 136: 3712—3723. PMID 15475410.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Zn2+-exporting+ATPase на US National Library of Medicine Medical Subject Headings (MeSH)
