16S rRNK (citozin967-C5)-metiltransferaza

16S rRNK (citozin967-C5)-metiltransferaza (EC 2.1.1.176, rsmB (gen), fmu (gen), 16S rRNK m5C967 metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:16S rRNK (citozin967-C5)-metiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

16S rRNK (citozin967-C5)-metiltransferaza
Identifikatori
EC broj2.1.1.176
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum
S-adenozil-L-metionin + citozin967 u 16S rRNK S-adenozil-L-homocistein + 5-metilcitozin967 u 16S rRNK

Ovaj enzim specifično metiliše citozin967 u C5 poziciji 16S rRNK.

Reference

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  1. ^ Tscherne, J.S., Nurse, K., Popienick, P., Michel, H., Sochacki, M. and Ofengand, J. (1999). „Purification, cloning, and characterization of the 16S RNA m5C967 methyltransferase from Escherichia coli”. Biochemistry. 38: 1884—1892. PMID 10026269. 
  2. ^ Gu, X.R., Gustafsson, C., Ku, J., Yu, M. and Santi, D.V. (1999). „Identification of the 16S rRNA m5C967 methyltransferase from Escherichia coli”. Biochemistry. 38: 4053—4057. PMID 10194318. 
  3. ^ Foster, P.G., Nunes, C.R., Greene, P., Moustakas, D. and Stroud, R.M. (2003). „The first structure of an RNA m5C methyltransferase, Fmu, provides insight into catalytic mechanism and specific binding of RNA substrate”. Structure. 11: 1609—1620. PMID 14656444. 

Literatura

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Spoljašnje veze

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