Alkohol dehidrogenaza (akceptor)
Alkohol dehidrogenaza (akceptor) (EC 1.1.99.8, primarno alkoholna dehidrogenaza, MDH, hinohemoproteinska alkoholna dehidrogenaza, hinoproteinska alkoholna dehidrogenaza, hinoprotein etanolna dehidrogenaza, alkohol:(akceptor) oksidoreduktaza) je enzim sa sistematskim imenom alkohol:akceptor oksidoreduktaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
Alkohol dehidrogenaza (akceptor) | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifikatori | |||||||||
EC broj | 1.1.99.8 | ||||||||
CAS broj | 37205-43-9 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
|
- primarni alkohol + akceptor aldehid + redukovani akceptor
Ovaj enzim je hinoprotein. On deluje na širok opseg primarnih alkohola, uključujući metanol (cf. EC 1.1.99.20, alkan-1-ol dehidrogenaza (akceptor)).
Reference
uredi- ^ Ameyama, M. & Adachi, O. (1982). „Alcohol dehydrogenase from acetic acid bacteria, membrane-bound”. Methods Enzymol. 89: 450—457.
- ^ Anthony, C. & Zatman, L.J. (1967). „The microbial oxidation of methanol. Purification and properties of the alcohol dehydrogenase of Pseudomonas sp. M27”. Biochem. J. 104: 953—959. PMID 6058112.
- ^ Duine, J.A., Frank, J. and Van Zeeland, J.K. (1979). „Glucose dehydrogenase from Acinetobacter calcoaceticus: a 'quinoprotein'”. FEBS Lett. 108: 443—446. PMID 520586.
- ^ Duine, J.A., Frank, J. and Verweil, P.E.J. (1980). „Structure and activity of the prosthetic group of methanol dehydrogenase”. Eur. J. Biochem. 108: 187—192. PMID 6250827.
- ^ Salisbury, S.A., Forrest, H.S., Cruse, W.B.T. and Kennard, O. (1979). „A novel coenzyme from bacterial primary alcohol dehydrogenases”. Nature (Lond.). 280: 843—844. PMID 471057.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
uredi- Alcohol+dehydrogenase+(acceptor) na US National Library of Medicine Medical Subject Headings (MeSH)