Bis(5'-nukleozil)-tetrafosfataza (asimetrična)
Bis(5'-nukleozil)-tetrafosfataza (asimetrična) (EC 3.6.1.17, bis(5'-guanozil)-tetrafosfataza, bis(5'-adenozil)-tetrafosfataza, diguanozintetrafosfataza (asimetrična), dinukleozidtetrafosfataza (asimetrična), diadenozin P1,P4-tetrafosfataza, dinukleozidna tetrafosfataza, 1-P,4-P-bis(5'-nukleozil)-tetrafosfatna nukleotidohidrolaza) je enzim sa sistematskim imenom P1,P4-bis(5'-nukleosil)-tetrafosfat nukleotidohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Bis(5'-nukleozil)-tetrafosfataza (asimetrična) | |||||||||
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Identifikatori | |||||||||
EC broj | 3.6.1.17 | ||||||||
CAS broj | 37289-29-5 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- P1,P4-bis(5'-guanozil) tetrafosfat + H2O GTP + GMP
Ovaj enzim takođe deluje na bis(5'-ksantozil)-tetrafosfat i, manjom brzinom, na bis(5'-adenozil)-tetrafosfat i bis(5'-uridil)-tetrafosfat.
Reference
uredi- ^ Jakubowski, H. & Guranowski, A. (1983). „Enzymes hydrolyzing ApppA and/or AppppA in higher plants. Purification and some properties of diadenosine triphosphatase, diadenosine tetraphosphatase, and phosphodiesterase from yellow lupin (Lupinus luteus) seeds”. J. Biol. Chem. 258: 9982—9989. PMID 6309793.
- ^ Vallejo, C.M., Lobatón, C.D., Quintanilla, M., Sillero, A. and Sillero, M.A.G. (1976). „Dinucleosidasetetraphosphatase in rat liver and Artemia salina”. Biochim. Biophys. Acta. 438: 304—309. PMID 181087.
- ^ Warner, A.H. & Finamore, F.J. (1965). „Isolation, purification, and characterization of P1,P4-diguanosine 5′-tetraphosphate asymmetrical-pyrophosphohydrolase from brine shrimp eggs”. Biochemistry. 4: 1568—1575. PMID 4955726.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
uredi- Bis(5'-nucleosyl)-tetraphosphatase+(asymmetrical) на US National Library of Medicine Medical Subject Headings (MeSH)