CDP-diacilglicerol—holin O-fosfatidiltransferaza
CDP-diacilglicerol—holin O-fosfatidiltransferaza (EC 2.7.8.24, CDP-diglicerid-holin O-fosfatidiltransferaza) je enzim sa sistematskim imenom CDP-diacilglicerol:holin O-fosfatidiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
CDP-diacilglicerol—holin O-fosfatidiltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.7.8.24 | ||||||||
CAS broj | 243666-86-6 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- CDP-diacilglicerol + holin CMP + fosfatidilholin
Za dejstvo ovog enzima je neophodan dvovalentni katjon Mn2+. Enzim funkcioniše u sa Mg2+.
Reference
uredi- ^ de Rudder, K.E.E., Sohlenkamp, C. and Geiger, O. (1999). „Plant-exudated choline is used for rhizobial membrane lipid biosynthesis by phosphatidylcholine synthase”. J. Biol. Chem. 274: 20011—20016. PMID 10391951.
- ^ Sohlenkamp, C., de Rudder, K.E.E., Röhrs, V., López-Lara, I.M. and Geiger, O. (2000). „Cloning and characterization of the gene for phosphatidylcholine synthase”. J. Biol. Chem. 275: 18919—18925. PMID 10858449.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
uredi- Phosphatidylcholine+synthase na US National Library of Medicine Medical Subject Headings (MeSH)