Diaminohidroksifosforibozilaminopirimidinska deaminaza
Diaminohidroksifosforibozilaminopirimidinska deaminaza (EC 3.5.4.26) je enzim sa sistematskim imenom 2,5-diamino-6-hidroksi-4-(5-fosfo-D-ribozilamino)pirimidin 2-aminohidrolaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Diaminohidroksifosforibozilaminopirimidinska deaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.4.26 | ||||||||
| CAS broj | 68994-19-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 2,5-diamino-6-hidroksi-4-(5-fosfo-D-ribozilamino)pirimidin + H2O 5-amino-6-(5-fosfo-D-ribozilamino)uracil + NH3
Supstrat je produkt enzima EC 3.5.4.25, GTP ciklohidrolaze II.
Reference
uredi- ^ Burrows, R.B. & Brown, G.M. (1978). „Presence of Escherichia coli of a deaminase and a reductase involved in biosynthesis of riboflavin”. J. Bacteriol. 136: 657—667. PMID 30756.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
uredi- Diaminohydroxyphosphoribosylaminopyrimidine+deaminase на US National Library of Medicine Medical Subject Headings (MeSH)
