FAD-AMP lijaza
FAD-AMP lijaza (EC 4.6.1.15, FMN ciklaza, FAD AMP-lijaza (formira ciklični-FMN)) je enzim sa sistematskim imenom FAD AMP-lijaza (formira riboflavin-ciklični-4',5'-fosfat).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| FAD-AMP lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.6.1.15 | ||||||||
| CAS broj | 208349-48-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- FAD AMP + riboflavin ciklični-4',5'-fosfat
Za dejstvo ovog enzima je neophodan Mn2+ ili Co2+.
Reference
uredi- ^ Fraiz, F.J., Pinto, R.M., Costas, M.J., Avalos, M., Canales, J., Cabezas, A. and Cameselle, J.C. (1998). „Enzymic formation of riboflavin 4′,5′-cyclic phosphate from FAD: evidence for a specific low-Km FMN cyclase in rat liver”. Biochem. J. 330: 881—888. PMID 9480905.
- ^ Cabezas, A., Pinto, R.M., Fraiz, F., Canales, J., Gonzalez-Santiago, S. and Cameselle, J.C. (2001). „Purification, characterization, and substrate and inhibitor structure-activity studies of rat liver FAD-AMP lyase (cyclizing): preference for FAD and specificity for splitting ribonucleoside diphosphate-X into ribonucleotide and a five-atom cyclic phosphodiester of X, either a monocyclic compound or a cis-bicyclic phosphodiester-pyranose fusion”. Biochemistry. 40: 13710—13722. PMID 11695920.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
uredi- FAD-AMP+lyase+(cyclizing) na US National Library of Medicine Medical Subject Headings (MeSH)
