FAD-AMP lijaza (EC 4.6.1.15, FMN ciklaza, FAD AMP-lijaza (formira ciklični-FMN)) je enzim sa sistematskim imenom FAD AMP-lijaza (formira riboflavin-ciklični-4',5'-fosfat).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

FAD-AMP lijaza
Identifikatori
EC broj4.6.1.15
CAS broj208349-48-8
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum
FAD AMP + riboflavin ciklični-4',5'-fosfat

Za dejstvo ovog enzima je neophodan Mn2+ ili Co2+.

Reference

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  1. ^ Fraiz, F.J., Pinto, R.M., Costas, M.J., Avalos, M., Canales, J., Cabezas, A. and Cameselle, J.C. (1998). „Enzymic formation of riboflavin 4′,5′-cyclic phosphate from FAD: evidence for a specific low-Km FMN cyclase in rat liver”. Biochem. J. 330: 881—888. PMID 9480905. 
  2. ^ Cabezas, A., Pinto, R.M., Fraiz, F., Canales, J., Gonzalez-Santiago, S. and Cameselle, J.C. (2001). „Purification, characterization, and substrate and inhibitor structure-activity studies of rat liver FAD-AMP lyase (cyclizing): preference for FAD and specificity for splitting ribonucleoside diphosphate-X into ribonucleotide and a five-atom cyclic phosphodiester of X, either a monocyclic compound or a cis-bicyclic phosphodiester-pyranose fusion”. Biochemistry. 40: 13710—13722. PMID 11695920. 

Literatura

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Spoljašnje veze

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