Kukurbitacin D23-reduktaza
Kukurbitacin D23-reduktaza (EC 1.3.1.5, NAD(P)H: kukurbitacin B Delta23-oksidoreduktaza) je enzim sa sistematskim imenom 23,24-dihidrokukurbitacin:NAD(P)+ Delta23-oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Kukurbitacin D23-reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.1.5 | ||||||||
| CAS broj | 37256-38-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 23,24-dihidrokukurbitacin B + NAD(P)+ kukurbitacin B + NAD(P)H + H+
Za rad ovog enzima je neophodan Mn2+. Fe2+ ili Zn2+ mogu da zemen Mn2+ u izvesnoj meri.
Reference
uredi- ^ Schabort, J.C. & Potgieter, D.J.J. (1968). „Cucurbitacin B Δ23-reductase from Cucurbita maxima. II. Cofactor requirements, enzyme kinetics, substrate specificity and other characteristics”. Biochim. Biophys. Acta. 151: 47—53. PMID 4384331.
- ^ Schabort, J.C., Potgieter, D.J.J. and de Villiers, V. (1968). „Cucurbitacin B Δ23-reductase from Cucurbita maxima. I. Assay methods, isolation and purification”. Biochim. Biophys. Acta. 151: 33—46. PMID 5640163.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
uredi- Cucurbitacin+Delta23-reductase na US National Library of Medicine Medical Subject Headings (MeSH)
