Kvercetin 3-O-metiltransferaza
Kvercetin 3-O-metiltransferaza (EC 2.1.1.76, flavonolna 3-O-metiltransferaza, flavonoidna 3-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:3,5,7,3',4'-pentahidroksiflavon 3-O-metiltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Kvercetin 3-O-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.76 | ||||||||
| CAS broj | 81295-55-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- S-adenozil-L-metionin + 3,5,7,3',4'-pentahidroksiflavon S-adenozil-L-homocistein + 3-metoksi-5,7,3',4'-tetrahidroksiflavon
Ovaj enzim je specifičan za kvercetin.
Reference
uredi- ^ De Luca, V., Brunet, G., Khouri, H., Ibrahim, R. and Hrazdina, G. (1982). „Flavonol 3-O-methyltransferase in plant-tissues”. Z. Naturforsch. 37: 134—135.
- ^ De Luca, V. & Ibrahim, R.K. (1985). „Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4′-O-methyltransferases”. Arch. Biochem. Biophys. 238: 596—605. PMID 3994393.
- ^ De Luca, V. & Ibrahim, R.K. (1985). „Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. II. Substrate interaction and product inhibition studies of flavonol 3-, 6-, and 4′-O-methyltransferases”. Arch. Biochem. Biophys. 238: 606—618. PMID 3994394.
- ^ Ibrahim, R.K. & De Luca, V. (1982). „Polymethylated flavonol synthesis is catalyzed by distinct O-methyltransferases”. Naturwissenschaften. 69: 41—42.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
uredi- Quercetin+3-O-methyltransferase na US National Library of Medicine Medical Subject Headings (MeSH)
